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Nrf2-Independent Anti-Inflammatory Effects of Dimethyl Fumarate: Challenges and Prospects in Developing Electrophilic Nrf2 Activators for Neurodegenerative Diseases

The NF-E2-related factor 2 (Nrf2)-antioxidant response element (ARE) pathway is a potential therapeutic target for central nervous system diseases. This review emphasizes the role of oxidative stress and neuroinflammation in neurodegenerative diseases, highlighting the therapeutic potential of Nrf2...

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Bibliografische gegevens
Hoofdauteurs: Yasuhiko Izumi, Yutaka Koyama
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2024-12-01
Reeks:Antioxidants
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Online toegang:https://www.mdpi.com/2076-3921/13/12/1527
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