Dimethyl Fumarate, an Approved Multiple Sclerosis Treatment, Reduces Brain Oxidative Stress in SIV-Infected Rhesus Macaques: Potential Therapeutic Repurposing for HIV Neuroprotection

Dimethyl fumarate (DMF), an antioxidant/anti-inflammatory drug approved for the treatment of multiple sclerosis, induces antioxidant enzymes, in part through transcriptional upregulation. We hypothesized that DMF administration to simian immunodeficiency virus (SIV)-infected rhesus macaques would in...

תיאור מלא

מידע ביבליוגרפי

Principais autores:	Yoelvis Garcia-Mesa, He N. Xu, Patricia Vance, Analise L. Gruenewald, Rolando Garza, Cecily Midkiff, Xavier Alvarez-Hernandez, David J. Irwin, Alexander J. Gill, Dennis L. Kolson
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	MDPI AG 2021-03-01
סדרה:	Antioxidants
נושאים:	SIV HIV-associated neurocognitive disorders fumaric acid esters dimethyl fumarate DMF oxidative stress
גישה מקוונת:	https://www.mdpi.com/2076-3921/10/3/416
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!