Targeting cuproptosis for cancer therapy: mechanistic insights and clinical perspectives
Abstract Cuproptosis is a newly identified form of cell death induced by excessive copper (Cu) accumulation within cells. Mechanistically, cuproptosis results from Cu-induced aggregation of dihydrolipoamide S-acetyltransferase, correlated with the mitochondrial tricarboxylic acid cycle and the loss...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BMC
2024-08-01
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| シリーズ: | Journal of Hematology & Oncology |
| 主題: | |
| オンライン･アクセス: | https://doi.org/10.1186/s13045-024-01589-8 |
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