Metabolic drivers of genome instability in cancer: mechanisms and therapeutic opportunities
Abstract Metabolic reprogramming and genome instability represent two fundamental hallmarks of cancer. Emerging studies now demonstrate that specific metabolic alterations directly fuel replication stress, DNA damage, and compromised DNA damage response. This underscores that metabolites are not mer...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2026-04-01
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| Serie: | Experimental Hematology & Oncology |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1186/s40164-026-00775-3 |
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