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Metabolic drivers of genome instability in cancer: mechanisms and therapeutic opportunities

Abstract Metabolic reprogramming and genome instability represent two fundamental hallmarks of cancer. Emerging studies now demonstrate that specific metabolic alterations directly fuel replication stress, DNA damage, and compromised DNA damage response. This underscores that metabolites are not mer...

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Furkejuvvon:
Bibliográfalaš dieđut
Váldodahkkit: Yu-Shun Wang, Li-Heng Qian, Cui-Cui Liu, Ke-Da Yu
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: BMC 2026-04-01
Ráidu:Experimental Hematology & Oncology
Fáttát:
Liŋkkat:https://doi.org/10.1186/s40164-026-00775-3
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