Loop2 Size Modification Reveals Significant Impacts on the Potency of α-Conotoxin TxID
α4/6-conotoxin TxID, which was identified from <i>Conus textile</i>, simultaneously blocks rat (r) α3β4 and rα6/α3β4 nicotinic acetylcholine receptors (nAChRs) with IC<sub>50</sub> values of 3.6 nM and 33.9 nM, respectively. In order to identify the effects of loop2 size on the potency of TxID, alan...
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| Principais autores: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
MDPI AG
2023-05-01
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| 叢編: | Marine Drugs |
| 主題: | |
| 在線閱讀: | https://www.mdpi.com/1660-3397/21/5/286 |
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