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Loop2 Size Modification Reveals Significant Impacts on the Potency of α-Conotoxin TxID

α4/6-conotoxin TxID, which was identified from <i>Conus textile</i>, simultaneously blocks rat (r) α3β4 and rα6/α3β4 nicotinic acetylcholine receptors (nAChRs) with IC<sub>50</sub> values of 3.6 nM and 33.9 nM, respectively. In order to identify the effects of loop2 size on the potency of TxID, alan...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jianying Dong, Panpan Zhang, Junjie Xie, Ting Xie, Xiaopeng Zhu, Dongting Zhangsun, Jinpeng Yu, Sulan Luo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI AG 2023-05-01
Saila:Marine Drugs
Gaiak:
Sarrera elektronikoa:https://www.mdpi.com/1660-3397/21/5/286
Etiketak: Etiketa erantsi
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