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CDSeq: A novel complete deconvolution method for dissecting heterogeneous samples using gene expression data.

Quantifying cell-type proportions and their corresponding gene expression profiles in tissue samples would enhance understanding of the contributions of individual cell types to the physiological states of the tissue. Current approaches that address tissue heterogeneity have drawbacks. Experimental...

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Bibliografische Detailangaben
Hauptverfasser: Kai Kang, Qian Meng, Igor Shats, David M Umbach, Melissa Li, Yuanyuan Li, Xiaoling Li, Leping Li
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2019-12-01
Schriftenreihe:PLoS Computational Biology
Online-Zugang:https://doi.org/10.1371/journal.pcbi.1007510
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