GPR65 promotes intestinal mucosal Th1 and Th17 cell differentiation and gut inflammation through downregulating NUAK2

Abstract G protein‐coupled receptor 65 (GPR65), a susceptibility gene for inflammatory bowel diseases (IBD), has been identified to promote Th17 cell pathogenicity and induce T cell apoptosis. However, the potential role of GPR65 in modulating CD4+ T cell immune responses in the pathogenesis of IBD...

Descripción completa

Detalles Bibliográficos

Autores principales:	Ritian Lin, Wei Wu, Huimin Chen, Han Gao, Xiaohan Wu, Gengfeng Li, Qiong He, Huiying Lu, Mingming Sun, Zhanju Liu
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Wiley 2022-03-01
Colección:	Clinical and Translational Medicine
Materias:	GPR65 inflammatory bowel diseases Th1 cells Th17 cells
Acceso en línea:	https://doi.org/10.1002/ctm2.771
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!