A mechanistic view of the role of E3 in sumoylation.
Sumoylation, the covalent attachment of SUMO (Small Ubiquitin-Like Modifier) to proteins, differs from other Ubl (Ubiquitin-like) pathways. In sumoylation, E2 ligase Ubc9 can function without E3 enzymes, albeit with lower reaction efficiency. Here, we study the mechanism through which E3 ligase RanB...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2010-08-01
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| coleção: | PLoS Computational Biology |
| Acesso em linha: | https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000913&type=printable |
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