Scalable (Enantioselective) Syntheses of Novel 3-Methylated Analogs of Pazinaclone, (<i>S</i>)-PD172938 and Related Biologically Relevant Isoindolinones

Herein, we report the application of an efficient and practical K₂CO₃ promoted cascade reaction of 2-acetylbenzonitrile in the synthesis of novel 3-methylated analogs of Pazinaclone and PD172938, belonging to isoindolinones heterocyclic class bearing a tetrasubstituted stereoce...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Antonia Di Mola, Giorgia Nicastro, Lorenzo Serusi, Rosanna Filosa, Mario Waser, Antonio Massa
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2022-09-01
Edice:	Molecules
Témata:	heterocycles asymmetric synthesis isoindolinones
On-line přístup:	https://www.mdpi.com/1420-3049/27/17/5647
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!