Scalable (Enantioselective) Syntheses of Novel 3-Methylated Analogs of Pazinaclone, (<i>S</i>)-PD172938 and Related Biologically Relevant Isoindolinones
Herein, we report the application of an efficient and practical K<sub>2</sub>CO<sub>3</sub> promoted cascade reaction of 2-acetylbenzonitrile in the synthesis of novel 3-methylated analogs of Pazinaclone and PD172938, belonging to isoindolinones heterocyclic class bearing a tetrasubstituted stereoce...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI AG
2022-09-01
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| Col·lecció: | Molecules |
| Matèries: | |
| Accés en línia: | https://www.mdpi.com/1420-3049/27/17/5647 |
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