Disruption of Mitochondrion-To-Nucleus Interaction in Deceased Cloned Piglets.

Most animals produced by somatic cell nuclear transfer (SCNT) are heteroplasmic for mitochondrial DNA (mtDNA). Oxidative phosphorylation (OXPHOS) in clones therefore requires the coordinated expression of genes encoded by the nuclear DNA and the two sources of mitochondria. Such interaction is rarel...

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Principais autores:	Joonghoon Park, Liangxue Lai, Melissa S Samuel, David Wax, Randall S Prather, Xiuchun Tian
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2015-01-01
coleção:	PLoS ONE
Acesso em linha:	http://europepmc.org/articles/PMC4466210?pdf=render
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