Differential roles of MAPK kinases MKK3 and MKK6 in osteoclastogenesis and bone loss.

Bone mass is maintained by osteoclasts that resorb bone and osteoblasts that promote matrix deposition and mineralization. Bone homeostasis is altered in chronic inflammation as well as in post-menopausal loss of estrogen, which favors osteoclast activity that leads to osteoporosis. The MAPK p38α is...

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書誌詳細

主要な著者:	David L Boyle, Deepa Hammaker, Meghan Edgar, Mario M Zaiss, Stefan Teufel, Jean Pierre David, Georg Schett, Gary S Firestein
フォーマット:	Artigo
言語:	Inglês
出版事項:	Public Library of Science (PLoS) 2014-01-01
シリーズ:	PLoS ONE
オンライン･アクセス:	http://europepmc.org/articles/PMC3882259?pdf=render
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