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Differential roles of MAPK kinases MKK3 and MKK6 in osteoclastogenesis and bone loss.

Bone mass is maintained by osteoclasts that resorb bone and osteoblasts that promote matrix deposition and mineralization. Bone homeostasis is altered in chronic inflammation as well as in post-menopausal loss of estrogen, which favors osteoclast activity that leads to osteoporosis. The MAPK p38α is...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: David L Boyle, Deepa Hammaker, Meghan Edgar, Mario M Zaiss, Stefan Teufel, Jean Pierre David, Georg Schett, Gary S Firestein
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science (PLoS) 2014-01-01
Saila:PLoS ONE
Sarrera elektronikoa:http://europepmc.org/articles/PMC3882259?pdf=render
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