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Toll-like receptor-4 coordinates the innate immune response of the kidney to renal ischemia/reperfusion injury.

Toll-like receptors (TLRs) can detect endogenous danger molecules released upon tissue injury resulting in the induction of a proinflammatory response. One of the TLR family members, TLR4, is constitutively expressed at RNA level on renal epithelium and this expression is enhanced upon renal ischemi...

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Principais autores: Wilco P Pulskens, Gwendoline J Teske, Loes M Butter, Joris J Roelofs, Tom van der Poll, Sandrine Florquin, Jaklien C Leemans
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2008-01-01
Serier:PLoS ONE
Online adgang:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0003596&type=printable
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