Presence of Infected Gr-1intCD11bhiCD11cint Monocytic Myeloid Derived Suppressor Cells Subverts T Cell Response and Is Associated With Impaired Dendritic Cell Function in Mycobacterium avium-Infected Mice

Myeloid-derived suppressor cells (MDSC) are immature myeloid cells with immunomodulatory function. To study the mechanism by which MDSC affect antimicrobial immunity, we infected mice with two M. avium strains of differential virulence, highly virulent Mycobacterium avium subsp. avium strain 25291 (...

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Detalhes bibliográficos

Principais autores:	Ketema Abdissa, Andreas Nerlich, Andreas Beineke, Nanthapon Ruangkiattikul, Vinay Pawar, Ulrike Heise, Nina Janze, Christine Falk, Dunja Bruder, Ulrike Schleicher, Christian Bogdan, Siegfried Weiss, Ralph Goethe
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2018-10-01
coleção:	Frontiers in Immunology
Assuntos:	MDSC non-tuberculous mycobacteria T cells dendritic cells iNOS Nos2
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fimmu.2018.02317/full
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