Presence of Infected Gr-1intCD11bhiCD11cint Monocytic Myeloid Derived Suppressor Cells Subverts T Cell Response and Is Associated With Impaired Dendritic Cell Function in Mycobacterium avium-Infected Mice

Myeloid-derived suppressor cells (MDSC) are immature myeloid cells with immunomodulatory function. To study the mechanism by which MDSC affect antimicrobial immunity, we infected mice with two M. avium strains of differential virulence, highly virulent Mycobacterium avium subsp. avium strain 25291 (...

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Bibliografski detalji

Glavni autori:	Ketema Abdissa, Andreas Nerlich, Andreas Beineke, Nanthapon Ruangkiattikul, Vinay Pawar, Ulrike Heise, Nina Janze, Christine Falk, Dunja Bruder, Ulrike Schleicher, Christian Bogdan, Siegfried Weiss, Ralph Goethe
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2018-10-01
Serija:	Frontiers in Immunology
Teme:	MDSC non-tuberculous mycobacteria T cells dendritic cells iNOS Nos2
Online pristup:	https://www.frontiersin.org/article/10.3389/fimmu.2018.02317/full
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