A carrier-free self-assembling nanovaccine comprising a STING agonist and antigenic peptides for controlled immune activation

The stimulator of interferon genes (STING) pathway plays a central role in antitumor immunity. However, the clinical application of cyclic dinucleotides (CDNs) as STING agonists is hampered by their poor stability and hydrophilicity. Critically, the systemic administration of free CDNs can lead to t...

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主要な著者:	Tian-Yang Wang, Hong-Guo Hu, Geng-Hui Feng, Jing-Yun Su, Shao-Hua Zhuo, Zhuo Huang, Yan-Mei Li
フォーマット:	Artigo
言語:	Inglês
出版事項:	Tsinghua University Press 2026-04-01
シリーズ:	Nano Research
主題:	sting pathway nanovaccine self-assembling peptides antigen presentation lymph node cancer immunotherapy
オンライン･アクセス:	https://www.sciopen.com/article/10.26599/NR.2025.94908278
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