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Sex effects in mouse prion disease incubation time.

Prion disease incubation time in mice is determined by many factors including PrP expression level, Prnp alleles, genetic background, prion strain and route of inoculation. Sex differences have been described in age of onset for vCJD and in disease duration for both vCJD and sporadic CJD and have al...

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Detalles Bibliográficos
Principais autores: Shaheen Akhtar, Adam Wenborn, Sebastian Brandner, John Collinge, Sarah E Lloyd
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Acceso en liña:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0028741&type=printable
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