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A flexible liposomal polymer complex as a platform of specific and regulable immune regulation for individual cancer immunotherapy

Abstract Background The applicability and therapeutic efficacy of specific personalized immunotherapy for cancer patients is limited by the genetic diversity of the host or the tumor. Side-effects such as immune-related adverse events (IRAEs) derived from the administration of immunotherapy have als...

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Principais autores: Chia-Hung Chen, Tzu-Han Weng, Hsiao-Hsuan Huang, Ling-Ya Huang, Kai-Yao Huang, Pin-Rong Chen, Kuang-Yu Yeh, Chi-Ting Huang, Yu-Tzu Chien, Po-Ya Chuang, Yu-Ling Lin, Nu-Man Tsai, Shih-Jen Liu, Yu-Cheng Su, Shun-Long Weng, Kuang-Wen Liao
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-01-01
Serier:Journal of Experimental & Clinical Cancer Research
Fag:
LPPC
Immunotherapy
Costimulatory molecules
personalized cancer therapy
Tumor heterogenicity
Online adgang:https://doi.org/10.1186/s13046-023-02601-8
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