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Antibiotic cocktail-induced changes in gut microbiota drive alteration of bile acid metabolism to restrain Th17 differentiation through the FXR–NLRP3 axis

Antibiotics influence both gut microbial composition and immune regulation, but the detailed mechanisms are still undefined. Shifts in the microbiome caused by antibiotic exposure can modulate immune activity through various pathways. Therefore, we aimed to explore how antibiotics affect immune-infl...

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Autores principales: Yue Shao-Yu, Di Niu, Jia Chen, Wei-Yi Li, Xu Wang, Qing-Wei Meng, Wei-Jie Song, Yi-Ge Yang, Hui Wang, Rong-Rong Li, Bo-Yang Li, Li-Gang Zhang, Chao-Jie Hu, Ling-Fan Xu, Hui-Hui Wang, Li Zhang, Chao-Zhao Liang, He-Xi Du
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis Group 2025-12-01
Colección:Gut Microbes
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Acceso en línea:https://www.tandfonline.com/doi/10.1080/19490976.2025.2582944
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