DNA replication protein Cdc45 directly interacts with PCNA via its PIP box in Leishmania donovani and the Cdc45 PIP box is essential for cell survival.

DNA replication protein Cdc45 is an integral part of the eukaryotic replicative helicase whose other components are the Mcm2-7 core, and GINS. We identified a PIP box motif in Leishmania donovani Cdc45. This motif is typically linked to interaction with the eukaryotic clamp proliferating cell nuclea...

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Ngā kaituhi matua:	Aarti Yadav, Varshni Sharma, Jyoti Pal, Pallavi Gulati, Manisha Goel, Udita Chandra, Neha Bansal, Swati Saha
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Public Library of Science (PLoS) 2020-05-01
Rangatū:	PLoS Pathogens
Urunga tuihono:	https://doi.org/10.1371/journal.ppat.1008190
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!