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Comparative evaluation of DNase-seq footprint identification strategies

DNase I is an enzyme preferentially cleaving DNA in highly accessible regions. Recently, Next-Generation Sequencing has been applied to DNase I assays (DNase-seq) to obtain genome-wide maps of these accessible chromatin regions.With high-depth sequencing, DNase I cleavage sites can be identified wit...

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Váldodahkkit: Iros eBarozzi, Pranami eBora, Marco J Morelli
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Frontiers Media S.A. 2014-08-01
Ráidu:Frontiers in Genetics
Fáttát:
Liŋkkat:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00278/full
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