Reproducible inference of transcription factor footprints in ATAC-seq and DNase-seq datasets using protocol-specific bias modeling

Abstract Background DNase-seq and ATAC-seq are broadly used methods to assay open chromatin regions genome-wide. The single nucleotide resolution of DNase-seq has been further exploited to infer transcription factor binding sites (TFBSs) in regulatory regions through footprinting. Recent studies hav...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Aslıhan Karabacak Calviello, Antje Hirsekorn, Ricardo Wurmus, Dilmurat Yusuf, Uwe Ohler
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2019-02-01
Edice:	Genome Biology
Témata:	ATAC-seq DNase-seq Footprinting Bias correction Reproducibility
On-line přístup:	http://link.springer.com/article/10.1186/s13059-019-1654-y
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!