Prevalence of actionable pharmacogenomic variants in Brazilian patients with cancer

IntroductionPharmacogenomic (PGx) variants can influence drug efficacy and safety, yet their prevalence in Latin American populations with cancer is underexplored. Our aim is to characterize the frequency and phenotypic distribution of actionable pharmacogenes in Brazilian patients with metastatic p...

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Autors principals:	Jaqueline B. Schuch, Mariana R. Botton, Angélica C. De Baumont, Giovana Curzel, Nathan A. Cadore, Cláudia Bordignon, Mahira L. Rosa, Vitor F. Vasconcellos, Lilian A. R. Barros, Cristiano P. Souza, Williams F. Barra, Daniela L. C. Louzeiro, Alessandra Notari, Juliana J. de Menezes, Pedro E. R. Liedke, Gláucio A. Bertollo, Aline B. L. Gongora, Henrique G. Ascenco, Eduardo Kowalski-Neto, Christina P. Oppermann, Gustavo Werutsky, Edilmar M. Santos, Flavio S. Brandão, Ruffo Freitas-Junior, Angélica Nogueira-Rodrigues, André L. C. Mancini, Marina Bessel, Gabriel S. Macedo, Daniela D. Rosa
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2026-03-01
Col·lecció:	Frontiers in Pharmacology
Matèries:	breast neoplasms exome sequencing pharmacogenetics pharmacogenomics prostate neoplasms
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fphar.2026.1736887/full
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