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Prevalence of actionable pharmacogenomic variants in Brazilian patients with cancer

IntroductionPharmacogenomic (PGx) variants can influence drug efficacy and safety, yet their prevalence in Latin American populations with cancer is underexplored. Our aim is to characterize the frequency and phenotypic distribution of actionable pharmacogenes in Brazilian patients with metastatic p...

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Hlavní autoři: Jaqueline B. Schuch, Mariana R. Botton, Angélica C. De Baumont, Giovana Curzel, Nathan A. Cadore, Cláudia Bordignon, Mahira L. Rosa, Vitor F. Vasconcellos, Lilian A. R. Barros, Cristiano P. Souza, Williams F. Barra, Daniela L. C. Louzeiro, Alessandra Notari, Juliana J. de Menezes, Pedro E. R. Liedke, Gláucio A. Bertollo, Aline B. L. Gongora, Henrique G. Ascenco, Eduardo Kowalski-Neto, Christina P. Oppermann, Gustavo Werutsky, Edilmar M. Santos, Flavio S. Brandão, Ruffo Freitas-Junior, Angélica Nogueira-Rodrigues, André L. C. Mancini, Marina Bessel, Gabriel S. Macedo, Daniela D. Rosa
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2026-03-01
Edice:Frontiers in Pharmacology
Témata:
breast neoplasms
exome sequencing
pharmacogenetics
pharmacogenomics
prostate neoplasms
On-line přístup:https://www.frontiersin.org/articles/10.3389/fphar.2026.1736887/full
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