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Diverse coactivator recruitment through differential PPARγ nuclear receptor agonism

The PPARγ nuclear receptor regulates the expression of genes involved in lipid and carbohydrate metabolism, and it has protective effects in some patients with type 2 diabetes. Nevertheless, the therapeutic value of the PPARγ nuclear receptor protein is limited due to the secondary effects...

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Principais autores: Fernando Lizcano, Diana Vargas
Format: Artigo
Sprog:Inglês
Udgivet: Sociedade Brasileira de Genética 2013-01-01
Serier:Genetics and Molecular Biology
Fag:
DNA binding proteins co-activator
gene expression
transcription
telmisartan
Online adgang:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572013000100020
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