CRP Enhances the Innate Killing Mechanisms Phagocytosis and ROS Formation in a Conformation and Complement-Dependent Manner

Phagocytosis and the formation of reactive oxygen species (ROS) in phagocytic leukocytes are an effective killing mechanism of the innate host defense. These cellular processes of innate immunity function in a complex interplay with humoral factors. C-reactive protein (CRP) in its activated, monomer...

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Autors principals:	Johannes Zeller, Balázs Bogner, Jurij Kiefer, David Braig, Oscar Winninger, Mark Fricke, Ebru Karasu, Karlheinz Peter, Markus Huber-Lang, Steffen Ulrich Eisenhardt
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2021-08-01
Col·lecció:	Frontiers in Immunology
Matèries:	innate immunity host defense C-reactive protein reactive oxygen species complement system complement inhibition
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.721887/full
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