An exploratory in vitro co-culture of enteric neurons and smooth muscle cells demonstrates neuronal contribution to muscle layer formation

Abstract Short Bowel Syndrome (SBS) is characterized by insufficient functional intestinal tissue capable of nutrient transport and absorption. Tissue engineering offers a promising strategy to restore intestinal function by reconstructing a bioengineered muscle layer. In this exploratory study, we...

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Detalhes bibliográficos

Principais autores:	Rasul Khasanov, María Ángeles Tapia-Laliena, Steven Schulte, Valentin Pavlov, Michael Boettcher, Lucas M. Wessel, Karl-Herbert Schäfer
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2026-02-01
coleção:	Scientific Reports
Assuntos:	Short bowel syndrome (SBS) Enteric nervous system (ENS) 3D tissue culture Tissue engineering Muscle layer
Acesso em linha:	https://doi.org/10.1038/s41598-026-39409-3
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