Urine miRNA signature as potential non-invasive diagnostic biomarker for Hirschsprung’s disease

Hirschsprung’s disease (HSCR) is characterized by congenital absence of ganglion cells in the gastrointestinal tract, which leads to impaired defecation, constipation and intestinal obstruction. The current diagnosis of HSCR is based on Rectal Suction Biopsies (RSBs), which could be complex in newbo...

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Bibliografske podrobnosti

Principais autores:	Abhijit Sreepada, Rasul Khasanov, Enas Zoheer Elkrewi, Carolina de la Torre, Judith Felcht, Ahmad A. Al Abdulqader, Richard Martel, Nicolás Andrés Hoyos-Celis, Michael Boettcher, Lucas M. Wessel, Karl-Herbert Schäfer, María Ángeles Tapia-Laliena
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2025-01-01
Serija:	Frontiers in Molecular Neuroscience
Teme:	Hirschsprung’s disease (HSCR) enteric nervous system (ENS) microRNA (miRNA) non-invasive diagnostic urine extracellular vesicles
Online dostop:	https://www.frontiersin.org/articles/10.3389/fnmol.2024.1504424/full
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