The Supraspliceosome — A Multi-Task Machine for Regulated Pre-mRNA Processing in the Cell Nucleus
Pre-mRNA splicing of Pol II transcripts is executed in the mammalian cell nucleus within a huge (21 MDa) and highly dynamic RNP machine — the supraspliceosome. It is composed of four splicing active native spliceosomes, each resembling an in vitro assembled spliceosome, which are connected by the pr...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Association for the Advancement of Science (AAAS)
2014-09-01
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| Collection: | Computational and Structural Biotechnology Journal |
| Sujets: | |
| Accès en ligne: | http://www.sciencedirect.com/science/article/pii/S2001037014000348 |
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