PARP Inhibition by Flavonoids Induced Selective Cell Killing to BRCA2-Deficient Cells
High consumption of dietary flavonoids might contribute to a reduction of cancer risks. Quercetin and its glycosides have PARP inhibitory effects and can induce selective cytotoxicity in BRCA2-deficient cells by synthetic lethality. We hypothesized that common flavonoids in diet naringenin, hesperet...
Gardado en:
| Principais autores: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI AG
2017-10-01
|
| Series: | Pharmaceuticals |
| Assuntos: | |
| Acceso en liña: | https://www.mdpi.com/1424-8247/10/4/80 |
| Tags: |
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|