Complex evolution of the GSTM gene family involves sharing of GSTM1 deletion polymorphism in humans and chimpanzees

Abstract Background The common deletion of the glutathione S-transferase Mu 1 (GSTM1) gene in humans has been shown to be involved in xenobiotic metabolism and associated with bladder cancer. However, the evolution of this deletion has not been investigated. Results In this study, we conducted compa...

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Hlavní autoři:	M. Saitou, Y. Satta, O. Gokcumen, T. Ishida
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2018-04-01
Edice:	BMC Genomics
Témata:	Copy number variation Structural variants Detoxifying gene family Primates Gene conversions Segmental duplications
On-line přístup:	http://link.springer.com/article/10.1186/s12864-018-4676-z
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