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ChemR23 signaling ameliorates brain injury via inhibiting NLRP3 inflammasome-mediated neuronal pyroptosis in ischemic stroke

Abstract Background Inflammatory response has been recognized as a pivotal pathophysiological process during cerebral ischemia. ChemR23 signaling is involved in the pathophysiology of various inflammatory diseases. Nevertheless, the role of ChemR23 signaling in ischemic stroke remains largely unknow...

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Principais autores: Lan Liu, Jiawei Zhang, Kaili Lu, Yaxuan Zhang, Xiaofeng Xu, Jiangshan Deng, Xiaojie Zhang, Haibing Zhang, Yuwu Zhao, Xiuzhe Wang
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2024-01-01
coleção:Journal of Translational Medicine
Assuntos:
Stroke
ChemR23
Pyroptosis
NLRP3 inflammasome
Neuron
Acesso em linha:https://doi.org/10.1186/s12967-023-04813-0
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