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ChemR23 activation reprograms macrophages toward a less inflammatory phenotype and dampens carcinoma progression

IntroductionTumor Associated Macrophages (TAM) are a major component of the tumor environment and their accumulation often correlates with poor prognosis by contributing to local inflammation, inhibition of anti-tumor immune response and resistance to anticancer treatments. In this study, we thus in...

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Principais autores: Margot Lavy, Vanessa Gauttier, Alison Dumont, Florian Chocteau, Sophie Deshayes, Judith Fresquet, Virginie Dehame, Isabelle Girault, Charlène Trilleaud, Stéphanie Neyton, Caroline Mary, Philippe Juin, Nicolas Poirier, Sophie Barillé-Nion, Christophe Blanquart
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-07-01
Serier:Frontiers in Immunology
Fag:
macrophage
cancer
ChemR23 receptor
agonist
antibody
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1196731/full
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