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Structural basis of αE-catenin–F-actin catch bond behavior

Cell-cell and cell-matrix junctions transmit mechanical forces during tissue morphogenesis and homeostasis. α-Catenin links cell-cell adhesion complexes to the actin cytoskeleton, and mechanical load strengthens its binding to F-actin in a direction-sensitive manner. Specifically, optical trap exper...

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Autors principals: Xiao-Ping Xu, Sabine Pokutta, Megan Torres, Mark F Swift, Dorit Hanein, Niels Volkmann, William I Weis
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications Ltd 2020-09-01
Col·lecció:eLife
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Accés en línia:https://elifesciences.org/articles/60878
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