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Dynamic autophosphorylation of mps1 kinase is required for faithful mitotic progression.

The spindle assembly checkpoint (SAC) is a surveillance mechanism monitoring cell cycle progression, thus ensuring accurate chromosome segregation. The conserved mitotic kinase Mps1 is a key component of the SAC. The human Mps1 exhibits comprehensive phosphorylation during mitosis. However, the rela...

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書誌詳細
主要な著者: Xinghui Wang, Huijuan Yu, Leilei Xu, Tongge Zhu, Fan Zheng, Chuanhai Fu, Zhiyong Wang, Zhen Dou
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2014-01-01
シリーズ:PLoS ONE
オンライン・アクセス:http://europepmc.org/articles/PMC4179234?pdf=render
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