ICE1 promotes the link between splicing and nonsense-mediated mRNA decay

The nonsense-mediated mRNA decay (NMD) pathway detects aberrant transcripts containing premature termination codons (PTCs) and regulates expression of 5–10% of non-aberrant human mRNAs. To date, most proteins involved in NMD have been identified by genetic screens in model organisms; however, the in...

Fuld beskrivelse

Bibliografiske detaljer

Principais autores:	Thomas D Baird, Ken Chih-Chien Cheng, Yu-Chi Chen, Eugen Buehler, Scott E Martin, James Inglese, J Robert Hogg
Format:	Artigo
Sprog:	Inglês
Udgivet:	eLife Sciences Publications Ltd 2018-03-01
Serier:	eLife
Fag:	nonsense-mediated mRNA decay siRNA screen exon junction complex RNA quality control ICE1 UPF3B
Online adgang:	https://elifesciences.org/articles/33178
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!