CPSF6 defines a conserved capsid interface that modulates HIV-1 replication.
The HIV-1 genome enters cells inside a shell comprised of capsid (CA) protein. Variation in CA sequence alters HIV-1 infectivity and escape from host restriction factors. However, apart from the Cyclophilin A-binding loop, CA has no known interfaces with which to interact with cellular cofactors. He...
Sparad:
| Huvudupphov: | , , , , , , , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
Public Library of Science (PLoS)
2012-01-01
|
| Serie: | PLoS Pathogens |
| Länkar: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002896&type=printable |
| Taggar: |
Inga taggar, Lägg till första taggen!
|