CPSF6 defines a conserved capsid interface that modulates HIV-1 replication.
The HIV-1 genome enters cells inside a shell comprised of capsid (CA) protein. Variation in CA sequence alters HIV-1 infectivity and escape from host restriction factors. However, apart from the Cyclophilin A-binding loop, CA has no known interfaces with which to interact with cellular cofactors. He...
Guardat en:
| Autors principals: | , , , , , , , , |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science (PLoS)
2012-01-01
|
| Col·lecció: | PLoS Pathogens |
| Accés en línia: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002896&type=printable |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|