Characterizing the Causal Pathway From Childhood Adiposity to Right Heart Physiology and Pulmonary Circulation Using Lifecourse Mendelian Randomization

Background Observational epidemiological studies have reported an association between childhood adiposity and altered cardiac morphology and function in later life. However, whether this is due to a direct consequence of being overweight during childhood has been difficult to establish, particularly...

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Главные авторы:	Genevieve M. Leyden, Helena Urquijo, Alun D. Hughes, George Davey Smith, Tom G. Richardson
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Wiley 2024-03-01
Серии:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Предметы:	cardiac physiology childhood adiposity lifecourse epidemiology Mendelian randomization vascular structure
Online-ссылка:	https://www.ahajournals.org/doi/10.1161/JAHA.123.030453
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