Abnormal DNA methylation within genes of the steroidogenesis pathway two years after paediatric critical illness and association with stunted growth in height further in time

Abstract Background Former critically ill children show an epigenetic age deceleration 2 years after paediatric intensive care unit (PICU) admission as compared with normally developing healthy children, with stunted growth in height 2 years further in time as physical correlate. This was particular...

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Bibliografiske detaljer

Principais autores:	Ilse Vanhorebeek, Grégoire Coppens, Fabian Güiza, Inge Derese, Pieter J. Wouters, Koen F. Joosten, Sascha C. Verbruggen, Greet Van den Berghe
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMC 2023-07-01
Serier:	Clinical Epigenetics
Fag:	Critical illness Paediatrics Children Steroidogenesis Sex steroids Aldosterone
Online adgang:	https://doi.org/10.1186/s13148-023-01530-9
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