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Amiodarone, Verapamil, or Diltiazem Use With Direct Oral Anticoagulants and the Risk of Hemorrhage in Older Adults

Background: Routinely used cardiac medications, based on pharmacokinetics, are hypothesized to increase drug levels of direct oral anticoagulants (DOACs), with the potential to increase the risk of hemorrhage. We set out to compare the risk for hemorrhage following initiation of amiodarone, verapami...

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Principais autores: Kevin Hill, MD, Ewa Sucha, MSc, Emily Rhodes, MPH, Sarah Bota, MPH, Gregory L. Hundemer, MD, MPH, Edward G. Clark, MD, MSc, Mark Canney, MD, PhD, Ziv Harel, MD, MPH, Tzu-Fei Wang, MD, MSc, Marc Carrier, MD, MSc, Harindra C. Wijeysundera, MD, PhD, Greg Knoll, MD, MSc, Manish M. Sood, MD, MSc
格式: Artigo
语言:Inglês
出版: Elsevier 2022-03-01
丛编:CJC Open
在线阅读:http://www.sciencedirect.com/science/article/pii/S2589790X21002997
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