Amiodarone, Verapamil, or Diltiazem Use With Direct Oral Anticoagulants and the Risk of Hemorrhage in Older Adults

Background: Routinely used cardiac medications, based on pharmacokinetics, are hypothesized to increase drug levels of direct oral anticoagulants (DOACs), with the potential to increase the risk of hemorrhage. We set out to compare the risk for hemorrhage following initiation of amiodarone, verapami...

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Autori principali:	Kevin Hill, MD, Ewa Sucha, MSc, Emily Rhodes, MPH, Sarah Bota, MPH, Gregory L. Hundemer, MD, MPH, Edward G. Clark, MD, MSc, Mark Canney, MD, PhD, Ziv Harel, MD, MPH, Tzu-Fei Wang, MD, MSc, Marc Carrier, MD, MSc, Harindra C. Wijeysundera, MD, PhD, Greg Knoll, MD, MSc, Manish M. Sood, MD, MSc
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2022-03-01
Serie:	CJC Open
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2589790X21002997
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