Identification of risk variants related to malignant tumors in children with birth defects by whole genome sequencing

Abstract Background Children with birth defects (BD) are more likely to develop cancer and the increased risk of cancer persists into adulthood. Prior population-based assessments have demonstrated that even non-chromosomal BDs are associated with at least two-fold increase of cancer risk. Identific...

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Prif Awduron:	Yichuan Liu, Hui-Qi Qu, Xiao Chang, Frank D Mentch, Haijun Qiu, Kenny Nguyen, Xiang Wang, Amir Hossein Saeidian, Deborah Watson, Joseph Glessner, Hakon Hakonarson
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	BMC 2022-11-01
Cyfres:	Biomarker Research
Pynciau:	Birth defect Pediatric cancer Whole genome sequencing
Mynediad Ar-lein:	https://doi.org/10.1186/s40364-022-00431-y
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