Copy number variations contribute to malignant tumor development in children with serious birth defects

There are two key signatures of pediatric cancers: (a) higher prevalence of germline alterations and (b) heterogeneity in alteration types. Recent population‐based assessments have demonstrated that children with birth defects (BDs) are more likely to develop cancer even without chromosomal anomalie...

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Hlavní autoři:	Yichuan Liu, Joseph Glessner, Hui‐Qi Qu, Xiao Chang, Haijun Qiu, Tiancheng Wang, Frank D. Mentch, Hakon Hakonarson
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2025-03-01
Edice:	Molecular Oncology
Témata:	birth defects copy number variations pediatric cancers whole‐genome sequencing
On-line přístup:	https://doi.org/10.1002/1878-0261.13718
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