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S1P/S1P<sub>2</sub> Signaling Axis Regulates Both NLRP3 Upregulation and NLRP3 Inflammasome Activation in Macrophages Primed with Lipopolysaccharide

The activation of NLRP3 inflammasome is a key factor for various inflammatory diseases. Here, we provide experimental evidence supporting the regulatory role of sphingosine-1-phosphate (S1P) in NLRP3 inflammasome activation in mouse bone-marrow-derived macrophages (BMDMs), along with the S1P recepto...

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Autors principals: Chi-Ho Lee, Ji Woong Choi
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2021-10-01
Col·lecció:Antioxidants
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Accés en línia:https://www.mdpi.com/2076-3921/10/11/1706
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