Effects of bisphosphonates after denosumab discontinuation and treatment effect heterogeneity using causal machine learning
Abstract Discontinuation of denosumab is associated with a rebound increase in osteoporotic fracture (OF) risk, and bisphosphonates (BPs) are commonly recommended as sequential therapy to mitigate this risk. However, their real-world effectiveness—and whether certain patients benefit more than other...
محفوظ في:
| المؤلفون الرئيسيون: | , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Nature Portfolio
2025-12-01
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| سلاسل: | Scientific Reports |
| الموضوعات: | |
| الوصول للمادة أونلاين: | https://doi.org/10.1038/s41598-025-28172-6 |
| الوسوم: |
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