Crystallographic data for Pyrococcus furiosus dolichylphosphate mannose synthase suggest that the enzyme could flip its glycolipid product
Abstract Dolichylphosphate mannose synthase (DPMS) performs an essential function by synthesizing the activated lipid-linked mannose intermediate used in protein glycosylation pathways. In eukaryotes and archaea, DPMS catalyzes the transfer of mannose from GDP-mannose to dolichylphosphate to generat...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2026-03-01
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| coleção: | Scientific Reports |
| Acesso em linha: | https://doi.org/10.1038/s41598-026-44343-5 |
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